Benign prostatic hyperplasia (BPH) Term Paper Example | Topics and Well Written Essays - 1500 words

Benign prostatic hyperplasia (BPH) - Term Paper Example Despite the fact that the common causes of benign prostatic hyperplasia (BPH) are not very clear, it is important to note that experts consider testosterone and other related hormones and major causes of BPH. This is a direct implication that BPH androgens have to present for BPH to occur in a patient’s body. This is evidence by the fact that boys who are castrated do not develop the disease when they age. This is because such people do not produce the hormone testosterone and other related hormones that are closely associated with this condition. It is difficult to prove that the occurrence of BPH is associated with some environmental conditions and lifestyle. However, there may be genetic links to the disease. This is because studies have indicated that sons of men who were previously diagnosed with BPH tend to be more probable to contract this disease. This is an implication of the presence of genetic link to the disease (Bachmann, & Rosette, 2011). The disease only affects males and is proven to affect only the older men. It has not been proven that BPH can affect boys under the age of 20 and it is for this reason that the disease is associated with older men. BPH begins with both the stromal cells and the epithelial cells undergoing hyperplasia. In the process, a number of fibroadenomatous nodules form in the prostate around its periurethral region. The progressive growth of the nodules displaces the fibro-muscular prostate peripherally and the condition progresses. This results into the lengthening and narrowing of the prostatic urethral lumen. As a result, the outflow of urine is gradually obstructed (In Kaplan et al, 2014). Increased pressure, which is associated with bladder distention and micturition, can progress to trabeculation, the formation of cellule and diverticulitis. During the progressive